Clifton Ragsdale, Ph.D.
Molecular Genetic Control of Brain Development and
The Ragsdale laboratory studies the molecular and
cellular mechanisms that control the proliferation, migration and
differentiation of embryonic brain cells. A major related project
in the laboratory is a collaboration with Prof. Luping Yu of the
Department of Chemistry to develop polymers for in vivo gene
delivery. These new polymer systems have the promise of
generating new information about transfection cell biology and yielding
novel vectors for gene delivery in experimental animals and in human
Gan, L., Olson, J.L., Ragsdale, C.W. and Yu, L. (2008) Poly(beta-aminosulfonamides) as gene delivery vectors: synthesis and in vitro screening. Chem. Commun. 2008, 573-575.
Domowicz, M.S., Sanders, T., Ragsdale, C.W. and Schwartz, N.B. (2008) Aggrecan is expressed by embryonic brain glia and regulates astrocyte development. Dev. Biol. 315, 114-124.
Hasan, K.B., Agarwala, S., and Ragsdale, C.W. (2010) PHOX2A regulation of oculomotor complex nucleogenesis. Development 137, 1205-1213.