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Appointments:
Professor
Department of Surgery
Section of Transplantation
Committee on Molecular Medicine/MPMM
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Education:
M.D., Duke University
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Contact:
Phone: (773) 702-6104
Fax: (773)
702-2126
E-Mail: jthistle@surgery.bsd.uchicago.edu
Address:
The University of Chicago
AMB J571, (MC 5026)
5812 South Ellis Avenue
Chicago, Illinois 60637
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Related Research Interests:
Transplantation
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J. Richard Thistlethwaite, Jr., M.D.
Treatment of Allograft Rejection
Research Summary
Dr. Thistlethwaite's PHD is in immunology, and he has more than 200
published research papers on transplantation, immunology and
anti-rejection medications. His research has focused on the T cell
receptor and co-receptors in an attempt to develop biological reagents
that can be used as drugs to prevent transplant rejection. He is
currently the principal investigator of a multi-center trial sponsored
by the Immune Tolerance Network and the National Institutes of Health
studying the mechanism by which immune tolerance develops following
clinical liver transplantation. He has received multiple other research
grants from the NIH in the past.
Selected Papers
Whitington PF, Emond JC, Black DD, Whitington SH, Boone P, Smith C,
Thistlethwaite JR, Broelsch CE. (1991). Indications for liver
transplantation in pediatric patients. Clin Transplant. 1991 Apr;5(2
part 2):155-60. Review. PMID: 10147638 [PubMed - indexed for MEDLINE]
Dachman AH, Newmark GM, Thistlethwaite JR Jr, Oto A, Bruce DS, Newell
KA. Imaging of pancreatic transplantation using portal venous and
enteric exocrine drainage. AJR Am J Roentgenol.
1998 Jul;171(1):157-63. PMID: 9648780 [PubMed - indexed for MEDLINE]
Szot GL, Zhou P, Rulifson I, Wang J, Guo Z, Kim O, Newel
KA, Thistlethwaite JR, Bluestone JA, Alegre ML. (2001). Different
mechanisms of cardiac allograft rejection in wildtype and
CD28-deficient mice. Am
J Transplant. 2001 May;1(1):38-46. PMID: 12095035 [PubMed -
indexed for MEDLINE]
Ross LF, Glannon W, Josephson MA, Thistlethwaite JR Jr.
(2002). Should all living donors be treated equally? Transplantation. 74(3):418-21;
discussion 421-2. PMID: 12177627 [PubMed - indexed for MEDLINE]
Meehan SM, Limsrichamrern S, Manaligod JR, Junsanto T,
Josephson MA, Thistlethwaite JR, Haas M. (2003). Platelets and
capillary injury in acute humoral rejection of renal allografts. Hum Pathol. 34(6):533-40. PMID:
12827606 [PubMed - indexed for MEDLINE]
Josephson MA, Schumm LP, Chiu MY, Marshall C,
Thistlethwaite JR, Sprague SM. (2004). Calcium and calcitriol
prophylaxis attenuates posttransplant bone loss. Transplantation. 78(8):1233-6.
PMID: 15502727 [PubMed - indexed for MEDLINE]
Poduval RD, Kadambi PV, Josephson MA, Cohn RA, Harland
RC, Javaid B, Huo D, Manaligod JR, Thistlethwaite JR, Meehan SM.
(2005). Implications of immunohistochemical detection of C4d along
peritubular capillaries in late acute renal allograft rejection. Transplantation. 79(2):228-35. PMID:
15665772 [PubMed - indexed for MEDLINE]
Losanoff
JE, Harland RC, Thistlethwaite JR, Garfinkel MR, Williams JW, Milner J,
Millis JM. (2006). Omega jejunoduodenal anastomosis for pancreas
transplant. J
Am Coll Surg. 202(6):1021-4. No abstract available. PMID:
16735221 [PubMed - indexed for MEDLINE]
Ross
LF, Zenios S, Thistlethwaite JR Jr. (2006). Shared decision
making in deceased-donor transplantation. Lancet.
368(9532):333-7. No abstract available. PMID: 16860703 [PubMed -
indexed for MEDLINE]
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Faculty and Research
Programs
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